A blood protein produced by the liver that increases in response to inflammation, used as a marker of systemic inflammation.
FULL EXPLANATION
C-reactive protein (CRP) is an acute-phase reactant produced by the liver in response to inflammation. High-sensitivity CRP (hs-CRP) testing can detect lower levels of this protein and is used to assess cardiovascular disease risk.
CRP levels rise rapidly in response to infection, injury, or inflammatory conditions and fall as inflammation resolves. Chronically elevated CRP indicates ongoing low-grade inflammation, which is associated with numerous chronic diseases.
WHY IT MATTERS
Chronic low-grade inflammation is linked to cardiovascular disease, diabetes, cancer, and accelerated aging. CRP is a practical marker for monitoring inflammatory status.
HOW TO IMPROVE
Reduce CRP through anti-inflammatory diet (omega-3s, vegetables, low processed foods), regular exercise, weight management, adequate sleep, and stress reduction.
NORMAL RANGES
Low cardiovascular risk: <1.0 mg/L. Average risk: 1.0-3.0 mg/L. High risk: >3.0 mg/L. Optimal: <0.5 mg/L. Acute values can exceed 100 mg/L.
RELATED TERMS
Cytokines
Signaling proteins released by cells that regulate immunity, inflammation, and cell communication throughout the body.
Gut Microbiome
The complex community of microorganisms living in the digestive tract that influences digestion, immunity, and overall health.
Omega-3 Index
A measure of omega-3 fatty acid levels in red blood cell membranes, reflecting long-term omega-3 status and cardiovascular risk.
Sleep Quality
A measure of how well sleep restores and recovers the body, beyond simple sleep duration.
More in Inflammation & Immunity
View all →Cytokines
Well-EstablishedSignaling proteins released by cells that regulate immunity, inflammation, and cell communication throughout the body.
Gut Microbiome
Emerging ResearchThe complex community of microorganisms living in the digestive tract that influences digestion, immunity, and overall health.
Omega-3 Index
Well-EstablishedA measure of omega-3 fatty acid levels in red blood cell membranes, reflecting long-term omega-3 status and cardiovascular risk.