EARLY ACCESS
Mixed Evidence

Metabolism Slows Dramatically With Age

Weight Management | November 16, 2025 | 1 sources

THE CLAIM

"Your metabolism drops significantly every decade after 30, making weight gain inevitable."

[EVIDENCE SUMMARY]

A 2021 Science study revolutionized our understanding of metabolism across the lifespan. Metabolism remains stable from ages 20-60 when adjusted for body composition. The perceived slowdown is largely due to muscle loss from decreased activity, not an inevitable metabolic decline. After 60, metabolism does decline by about 0.7% per year.

The Groundbreaking 2021 Study

Researchers analyzed data from over 6,400 people aged 8 days to 95 years using doubly labeled water, the gold standard for measuring metabolism. They found four distinct metabolic phases: infancy (rapid increase), childhood to age 20 (gradual decline), 20-60 (stable), and 60+ (slow decline).

Key Finding

Between ages 20 and 60, metabolism remains remarkably stable when adjusted for body composition. The commonly blamed "age-related metabolic slowdown" is largely muscle loss from inactivity.

What Actually Happens With Age

  • Physical activity typically decreases
  • Muscle mass decreases without resistance training
  • Less muscle means lower resting metabolic rate
  • These factors are modifiable through lifestyle

[KEY TAKEAWAYS]

  • Metabolism stays stable from age 20-60 when adjusted for body composition
  • Muscle loss from inactivity, not aging itself, slows metabolism
  • Resistance training can prevent age-related muscle loss
  • After 60, metabolism declines about 0.7% per year

[SOURCES] (1)

1

Daily energy expenditure through the human life course

Pontzer H, et al.

Science 2021 High credibility
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