Grade B
Rct
Creatine and Brain Energy: Cognitive Enhancement RCT
RCT examining creatine supplementation effects on brain phosphocreatine levels, working memory, and cognitive performance under stress.
Published 2024
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[STUDY DETAILS]
- Study Type
- Rct
- Quality Grade
- B
- Publication Year
- 2024
- Category
- Mental Health & Cognition
Summary
6-week RCT (n=48) found 5g creatine daily increased brain PCr levels by 9.2% (MRS imaging) and improved working memory performance under sleep deprivation by 15%.
Key Findings
1. Brain phosphocreatine +9.2%
2. Working memory +15% under stress
3. Most benefit during cognitive demand
4. Vegetarians showed larger effects