Grade B
Meta analysis
Artificial Sweeteners and Gut Microbiome: Systematic Review
Review of artificial sweetener effects on gut microbiota composition, glucose tolerance, and metabolic health markers.
Published 2024
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[STUDY DETAILS]
- Study Type
- Meta analysis
- Quality Grade
- B
- Publication Year
- 2024
- Category
- Nutrition & Diet
Summary
Review of 34 studies found sucralose and saccharin alter gut microbiome composition. Clinical significance unclear; some individuals show impaired glucose tolerance while others unaffected.
Key Findings
1. Sucralose reduces beneficial bacteria 50%
2. Saccharin induces glucose intolerance in ~40%
3. Stevia appears more neutral
4. Individual responses highly variable