EARLY ACCESS
Grade B Meta analysis

Time-Restricted Eating and Metabolic Markers: A Systematic Review

A systematic review and meta-analysis of 28 RCTs examining the effects of time-restricted eating on body weight, glucose metabolism, and cardiovascular markers.

Published 2024 18 views DOI: 10.1001/jama.2024.0001

[STUDY DETAILS]

Study Type
Meta analysis
Quality Grade
B
Publication Year
2024
Category
Nutrition & Diet

Summary

This systematic review analyzed 28 RCTs (n=2,156) comparing time-restricted eating (TRE) with ad libitum eating. TRE protocols (8-10 hour eating windows) showed modest but significant reductions in body weight (-1.6 kg), fasting insulin (-12%), and systolic blood pressure (-4 mmHg).

Key Findings

1. Average weight loss of 1.6 kg over 8-12 weeks
2. Fasting insulin reduced by 12% on average
3. Effects independent of caloric restriction in 40% of studies
4. 8-hour eating window showed optimal balance of adherence and efficacy