DHEA-S

DHEA-S testing is straightforward and involves a simple blood test that can be performed at most laboratories or healthcare facilities [1]. The test measures the concentration of DHEA-S in your bloodstream and provides valuable information about your adrenal gland function.

**Test Procedure:**
The DHEA-S test requires a blood sample drawn from a vein, typically in your arm [4]. The procedure is quick and involves inserting a needle to collect blood, which some people may find slightly uncomfortable, but any pain is usually brief and minimal. Unlike some hormone tests, DHEA-S testing doesn't require special timing or multiple samples.

**Preparation Requirements:**
Minimal preparation is needed for DHEA-S testing [4]. You don't need to fast, though some laboratories may recommend it if other tests are being performed simultaneously. However, it's important to inform your healthcare provider if you're taking any vitamins or supplements containing DHEA or DHEA-sulfate, as these can affect your results.

**Optimal Testing Conditions:**
While DHEA-S levels remain relatively stable throughout the day compared to other hormones like cortisol, many healthcare providers prefer to collect samples in the morning for consistency. The hormone's stability means that a single measurement is usually sufficient to assess your status, unlike hormones that fluctuate significantly throughout the day.

**Result Reporting:**
Results are typically reported in micrograms per deciliter (μg/dL) or micromoles per liter (μmol/L) [4]. The test may be ordered individually to assess adrenal function or as part of comprehensive hormone panels when evaluating symptoms like fatigue, mood changes, or sexual dysfunction.

**When Testing is Recommended:**
Healthcare providers may order DHEA-S testing if you have symptoms suggesting adrenal disorders, unexplained fatigue, mood changes, or signs of hormonal imbalance [1]. The test is also used to monitor treatment response in patients receiving DHEA supplementation.