LH

LH measurement involves several testing methods, each suited for different clinical and personal needs. The most common and accurate method is blood testing, which requires a simple venous blood draw typically performed in a healthcare facility or laboratory [1]. These blood tests use sophisticated immunoassay techniques to measure LH concentration, with results reported in international units per liter (IU/L).

Timing is crucial for LH testing, particularly in women of reproductive age. For baseline LH levels, testing can occur at any time, but for specific diagnostic purposes, healthcare providers may request testing on particular days of the menstrual cycle. For example, testing during the early follicular phase (days 3-5 of the cycle) provides baseline levels, while testing around mid-cycle can capture the LH surge.

Urine-based LH testing offers a convenient alternative, particularly for home monitoring. Ovulation prediction kits (OPKs) detect LH in urine and are widely used by individuals tracking their fertility. These at-home test strips can identify the LH surge that precedes ovulation by 12-36 hours, making them valuable tools for family planning or conception efforts.

The laboratory analysis process involves immunoassays that use antibodies specific to LH to measure hormone concentration accurately. Modern testing methods are highly sensitive and can detect even small changes in LH levels, providing precise information for clinical decision-making.

For optimal accuracy, patients should follow specific preparation guidelines. While no special preparation is typically required for LH blood tests, it's important to inform healthcare providers about any medications, particularly hormonal contraceptives or fertility treatments, as these can affect LH levels. Women should also track their menstrual cycle timing to ensure appropriate test timing for their specific diagnostic needs.